Bioanalytical Services



Bioanalysis has contributed substantially to IPRC's leading position as an internationally recognized CRO



Our laboratories have the capability to develop and validate analytical methods for a variety of drug substances and metabolites using sophisticated high-throughput technologies.  IPRC utilizes a wide range of techniques available for bioanalysis, e.g., LCMSMS, LCMS, UPLC and HPLC.


Our staff, chemists holding Ph.D., MS or Bachelor of Science degrees have years of experience in this field.  Some of our staff are editorial members and / or referees of internationally distinguished journals. Our chemists handle Applied Biosystems APIs (3000, 4000, 4500 & 6500) and Waters Quattro Premier triple quadrupole stations, as well, manage UPLC and HPLC connected to UV, Florescence or ECD detectors. Watson LIMSTM is used for lab information management.


Our qualified and trained chemists working at the analytical laboratories, distributed into five teams, have the ability to handle more than five projects at the same time. Our team has the capacity to conduct more than 100 BE/ BA/ PK studies per year adhering to the highest quality standards and in accordance with GLP and international regulations. We have developed and validated more than 300 analytical methods and the list increases daily.




List of Validated Methods




CompoundMethodology
Aceclofenac HPLC/UV
Acenocoumarol - R LC/MS/MS
Acenocoumarol - S LC/MS/MS
Acetaminophen HPLC/UV, LC/MS/MS
Acetaminophen Cysteine LC/MS/MS
Acetaminophen Glucuronide LC/MS/MS
Acetaminophen Glutathione LC/MS/MS
Acetaminophen Mercaptaturate LC/MS/MS
Acetaminophen Sulfate LC/MS/MS
Acetylsalicylic acid LC/MS/MS
Acyclovir HPLC/UV
Alendronate HPLC/FL
Alfuzosin LC/MS/MS
Allepurinol HPLC/UV
Almotriptan LC/MS/MS
Alogliptin LC/MS/MS
Alprazolam LC/MS/MS
Ambrisentan LC/MS/MS
Amiloride LC/MS/MS
Amiodarone HPLC/UV
Amitriptyline LC/MS/MS
Amlodipine LC/MS/MS
Amoxicillin LC/MS/MS
Anagrelide LC/MS/MS
Apomorphine LC/MS/MS
Apremilast LC/MS/MS
Aripiprazole LC/MS/MS
Atenolol HPLC/FL
Atomoxetine LC/MS/MS
Atorvastain LC/MS/MS
Atorvastain, ortho-Hydroxy LC/MS/MS
Atorvastain, para-Hydroxy LC/MS/MS
Azilsartan LC/MS/MS
Azithromycin LC/MS/MS
Baclofen LC/MS/MS
Benazepril LC/MS/MS
Benazeprilat LC/MS/MS
Benserazide LC/MS/MS
Betahistine, 2-Pyridylacetic acid LC/MS/MS
Betamethasone LC/MS/MS
Betamethasone actate LC/MS/MS
Betamethasone phosphate LC/MS/MS
Bisoprolol LC/MS/MS
Budesonide LC/MS/MS
Buprenorphin LC/MS/MS
Buprenorphin, Norbuprenorphin LC/MS/MS
Bupropion HPLC/UV
Cabergoline LC/MS/MS
Caffeine LC/MS/MS
Candesartan LC/MS/MS
Captopril LC/MS/MS
Carbamazepine HPLC/UV
Carbamazepine 10, 11-epoxide HPLC/UV
Carbidopa LC/MS/MS
Carbocisteine LC/MS/MS
Carisoprodol LC/MS/MS
Carvedilol LC/MS/MS
Carvedilol, 4-Hydroxy LC/MS/MS
Cefaclor HPLC/UV
Cefadroxil HPLC/UV
Cefdinir LC/MS/MS
Cefixime HPLC/UV
Cefpodoxime HPLC/UV, LC/MS/MS
Cefprozil (E) HPLC/UV
Cefprozil (Z) HPLC/UV
Cefuroxime HPLC/UV
Celecoxib HPLC/UV
Cephalexin HPLC/UV
Cetirizine LC/MS/MS
Chlordiazepoxide LC/MS/MS
Chlorpheniramine HPLC/UV
Cilostazole LC/MS/MS
Cinacalcet LC/MS/MS
Ciprofloxacin HPLC/FL
Citalopram LC/MS
Clarithromycin LC/MS/MS
Clavulanic acid LC/MS/MS
Clindamycin HPLC/UV
Clomiphene LC/MS/MS
Clonazepam LC/MS/MS
Clopidogrel LC/MS/MS
Clopidogrel carboxylic acid LC/MS/MS
Codeine LC/MS/MS
Codeine-6-Glucuronide LC/MS/MS
Colchicine LC/MS/MS
Cotinine LC/MS/MS
Cyamemazine LC/MS/MS
Cyamemazine sulfoxide LC/MS/MS
Cyamemazine, N-desmethyl LC/MS/MS
Cyclizine LC/MS/MS
Cyclobenzaprine LC/MS/MS
Cyclosporin A LC/MS
Cyproheptadine LC/MS/MS
Dabigatran LC/MS/MS
Dalfampridine LC/MS/MS
Dapagliflazone LC/MS/MS
Dapoxetine LC/MS/MS
Dasatinib LC/MS/MS
Deferasirox LC/MS/MS
Desloratadine LC/MS/MS
Desmethyl, mebeverine acid LC/MS/MS
Diazepam LC/MS/MS
Diazepam, Desmethyl LC/MS/MS
Diclofenac HPLC/UV, LC/MS/MS
Diethylfumarate LC/MS/MS
Dihydroergotamine LC/MS/MS
Diltiazem HPLC/UV
Dimethylfumarate LC/MS/MS
Dipyridamole HPLC/FL
Disloratadine, 3-Hydroxy LC/MS/MS
Donepezil LC/MS/MS
Doxycycline HPLC/UV
Drotaverine LC/MS/MS
Duloxetine LC/MS/MS
Dutasteride LC/MS/MS
Eletriptan LC/MS/MS
Emtricitabine LC/MS/MS
Enalapril LC/MS/MS
Enalaprilat LC/MS/MS
Enoxacin HPLC/FL
Entecavir LC/MS/MS
Erlotinib LC/MS/MS
Erythromycin HPLC/EC
Escitalopram LC/MS/MS
Esomeprazole LC/MS/MS
Eszopiclone LC/MS/MS
Ethambutol LC/MS/MS
Etoricoxib HPLC/UV
Everolimus LC/MS/MS
Ezetimibe (Free) LC/MS/MS
Ezetimibe (Total) LC/MS/MS
Famotidine HPLC/UV
Febuxostat HPLC/FL
Fenofibric acid LC/MS/MS
Fexofenadine LC/MS/MS
Finasteride LC/MS/MS
Fingolimod LC/MS/MS
Fingolimod Phosphate LC/MS/MS
Flucloxacillin LC/MS/MS
Fluconazole HPLC/UV
Fluoxetine LC/MS/MS
Fluticasone LC/MS/MS
Fluvastatin LC/MS/MS
Formoterol LC/MS/MS
Fosinoprilat LC/MS/MS
Furazidin HPLC/UV
Furosemide HPLC/FL
Gabapentin HPLC/UV
Gatifloxacine HPLC/FL
Gemfibrozil HPLC/FL
Gliclazide LC/MS/MS
Glimepiride LC/MS/MS
Glyburide LC/MS/MS
Glycopyrronium LC/MS/MS
Hydrochlorothiazide LC/MS/MS
Hydrocortisone HPLC/UV
Ibrutinib LC/MS/MS
Ibuprofen HPLC/UV, LC/MS/MS
Imidapril LC/MS
Imidaprilat LC/MS
Indapamide LC/MS/MS
Indomethacin HPLC/UV
Irbesartan HPLC/FL
Isoniazid LC/MS/MS
Isosorbide dinitrate LC/MS/MS
Isosorbide-2-mononitrate LC/MS/MS
Isosorbide-5-mononitrate LC/MS/MS
Itraconazole LC/MS/MS
Itraconazole, Hydroxy LC/MS/MS
Ivabradine LC/MS/MS
Ketoconazole HPLC/FL
Ketotifen LC/MS
Lamivudine HPLC/UV
Lamotrigine HPLC/UV
Lansoprazole HPLC/UV
Leflunomide-M HPLC/UV
Lenalidomide LC/MS/MS
Lercanidipine LC/MS/MS
Levetiracetam HPLC/UV
Levocetirizine LC/MS/MS
Levodopa LC/MS/MS
Levofloxacin HPLC/FL
Lisinopril LC/MS/MS
Loperamide LC/MS/MS
Loratadine LC/MS/MS
Lornoxicam LC/MS/MS
Losartan LC/MS/MS
Losartan carboxylic acid LC/MS/MS
Lovastatin LC/MS/MS
Lovastatin, Hydroxy LC/MS/MS
Mebeverine acid LC/MS/MS
Mefenamic acid HPLC/UV
Mefloquine LC/MS
Melatonin LC/MS/MS
Meloxicam HPLC/UV
Memantine LC/MS/MS
Mertazepine LC/MS/MS
Metaxalone LC/MS/MS
Metformin HPLC/UV
Methyldopa LC/MS/MS
Metoprolol LC/MS/MS
Metronidazole HPLC/UV, LC/MS/MS
Metronidazole-OH LC/MS/MS
Miglustat LC/MS/MS
Minocycline HPLC/UV
Mirabegron LC/MS/MS
Mirabegron LC/MS/MS
Modafinil HPLC/UV
Monomethyl Fumarate LC/MS/MS
Montelukast HPLC/FL
Moxifloxacin HPLC/FL
Mycophenolate Mofetil LC/MS/MS
Mycophenolic acid HPLC/UV
Naloxone LC/MS/MS
Naproxen HPLC/UV
Nateglinide LC/MS/MS
Nicorandil LC/MS/MS
Nicotine LC/MS/MS
Nifedipine HPLC/UV, LC/MS
Nitisinone LC/MS/MS
Norfloxacin HPLC/FL
Nortriptyline LC/MS/MS
Olanzapine LC/MS/MS
Olmesartan LC/MS/MS
Omeprazole HPLC/UV
Ondansetron LC/MS/MS
Oseltamivir LC/MS/MS
Oseltamivir acid LC/MS/MS
Ospemifene LC/MS/MS
Oxypurinol HPLC/UV
Palbociclib LC/MS/MS
Pantoprazole LC/MS/MS
Paroxitine LC/MS/MS
Pazopanib LC/MS/MS
Penicilin V LC/MS/MS
Pheniramine LC/MS/MS
Phenylephrine LC/MS/MS
Phenylpropanolamine HPLC/UV
Phenyramidol LC/MS/MS
Phenytoin HPLC/UV
Pioglitazone LC/MS/MS
Pioglitazone, Hydroxy LC/MS/MS
Pirfenidone LC/MS/MS
Piroxicam HPLC/UV
Pitavastatin LC/MS/MS
Prasugrel LC/MS/MS
Pravastatin LC/MS/MS
Pregabaline LC/MS/MS
Pseudoephedrine LC/MS/MS
Pyrazinamide LC/MS/MS
Pyridylacetic acid LC/MS/MS
Quetiapine LC/MS/MS
Raloxifene LC/MS/MS
Raloxifene 4'-Glucuronide LC/MS/MS
Ramipril LC/MS/MS
Ramiprilat LC/MS/MS
Ranitidine HPLC/UV
Ranolazine LC/MS/MS
Repaglinide LC/MS/MS
Ribavirin LC/MS/MS
Rifampicin LC/MS/MS
Riluzole LC/MS/MS
Risperidone LC/MS/MS
Risperidone, 9-Hydroxy LC/MS/MS
Rivaroxaban LC/MS/MS
Roflumilast LC/MS/MS
Rosiglitazone HPLC/FL
Rosuvastatin LC/MS/MS
Sacubitril LC/MS/MS
Salbutamol LC/MS
Salicylic acid LC/MS/MS
Salicylic acid HPLC/UV
Salmeterol LC/MS/MS
Saxagliptin LC/MS/MS
Saxagliptin , 5-Hydroxy LC/MS/MS
Sertraline LC/MS/MS
Sibutramine LC/MS/MS
Sibutramine, Di desmethyl LC/MS/MS
Sibutramine, Mono desmethyl LC/MS/MS
Sildenafil LC/MS/MS
Sildenafil, Des methyl LC/MS/MS
Silodosin LC/MS/MS
Simvastatin, Hydroxy LC/MS/MS
Simvastatine LC/MS/MS
Sitagliptin LC/MS/MS
Sofosbuvir LC/MS/MS
Sofosbuvir Metabolite GS331007 LC/MS/MS
Spiramycin LC/MS/MS
Sulfamethizole HPLC/UV
Sulfamethoxazole HPLC/UV
Sulpiride HPLC/FL
Sumatriptan LC/MS/MS
Tadalafil LC/MS/MS
Telmisartan LC/MS/MS
Temazepam LC/MS/MS
Tenofovir LC/MS/MS
Tenoxicam HPLC/UV
Terazocin HPLC/FL
Terbinafine LC/MS/MS
Thiamine LC/MS/MS
Ticagrelor LC/MS/MS
Ticagrelor Deshydroxyethoxy LC/MS/MS
Ticlopidine HPLC/UV
Tiotropium LC/MS/MS
Tizanidine LC/MS/MS
Tolperisone LC/MS/MS
Topiramate LC/MS/MS
Tramadol LC/MS/MS
Tramadol, O-Desmethyl LC/MS/MS
Trandolapril LC/MS/MS
Trandolaprilat LC/MS/MS
Triamcinolone acetonide LC/MS/MS
Trimethoprim HPLC/UV
Valacyclovir LC/MS/MS
Valproic acid LC/MS
Valsartan LC/MS/MS
Vardenafil LC/MS/MS
Venlafaxine LC/MS/MS
Venlafaxine, O,D-Venlafaxine LC/MS/MS
Verapamil LC/MS/MS
Verapamil, Norverapamil LC/MS/MS
Veratric acid LC/MS/MS
Vildagliptin LC/MS/MS
Zolpidem LC/MS/MS